What was published
Nature’s journal Eye has published an Image Article titled “Autosomal recessive best disease mimicking chronic central serous chorioretinopathy.” The report is authored by Ahmet Peçen, Selda Çelik Dülger and Mehmet Yasin Teke of Ankara Etlik City Hospital in Ankara, Turkey, and was published online on October 5, 2026.
Based on the publicly available publisher preview, the article presents multimodal retinal imaging and describes a clinical situation in which autosomal recessive Best disease resembled chronic central serous chorioretinopathy. The full clinical narrative, patient history, imaging interpretation, genetic findings, testing details and management information are not included in the available preview.
Why this report may matter
The title highlights the possibility of diagnostic overlap between an inherited retinal condition—autosomal recessive Best disease—and chronic central serous chorioretinopathy. For people with inherited retinal disease, families, and eye-care professionals, this is a reminder that retinal appearances may sometimes resemble those of another condition.
However, the available material does not provide enough information to identify which particular imaging features led the authors to their conclusion, how the diagnosis was established, or whether genetic testing was performed. It also does not describe how often this type of overlap occurs. The article should therefore be understood as a published image-based case report rather than evidence about the frequency of misdiagnosis, the best diagnostic approach, or outcomes for people with similar retinal findings.
What evidence is available
The publisher preview confirms that the article includes a figure described as “Multimodal retinal imaging.” It also states that data supporting the Image Article may be requested from the corresponding author, subject to a reasonable request.
The authors list no competing interests. According to the publication record, the manuscript was received on August 16, 2026, revised on August 20, accepted on September 24, and published October 5, 2026.
Because the accessible page is largely limited to publication details and does not include the full article text, no further conclusions can be drawn from the preview about the individual described in the report. In particular, the available source does not support claims about treatment, prognosis, safety, effectiveness of any intervention, or implications for other patients.
Limitations
This is an Image Article, and the public preview provides only limited information. It does not disclose the patient’s symptoms, age, family history, disease course, diagnostic work-up, retinal imaging findings beyond the figure label, or follow-up. It also does not provide comparative data or a broader patient series.
As a result, the report may be of interest as an example of a potential diagnostic look-alike, but it cannot on its own establish clinical guidance. People with questions about an inherited retinal diagnosis or retinal imaging findings should discuss them with their qualified eye-care team.
Publisher source
Nature / Eye: Autosomal recessive best disease mimicking chronic central serous chorioretinopathy