Common Symptoms of Bardet-Biedl Syndrome

Common Symptoms of Bardet-Biedl Syndrome Understanding How BBS Affects the Body Bardet-Biedl Syndrome (BBS) is often referred to as a “multisystem disorder” because it affects many parts of the body in a wide variety of ways. Understanding the common symptoms can help individuals and families recognize early signs and seek proper diagnosis and care. 1. Vision Loss (Retinal Dystrophy) The most consistent and often earliest symptom of BBS is progressive vision loss. This is due to a condition called retinitis pigmentosa , which affects the retina—the light-sensitive tissue at the back of the eye. Symptoms may begin with night blindness in childhood Peripheral vision loss follows, often leading to tunnel vision In many cases, complete blindness occurs in adulthood 2. Kidney Abnormalities Up to 80% of individuals with BBS experience some form of kidney problem. These can range from mild structural differences to serious complications that affect kidney function. Increased risk of chronic kidney disease Monitoring and early intervention are crucial to protect long-term health 3. Obesity C